Read the Medication Guide that comes with you or your family member�s antidepressant medicine. This Medication Guide is only about the risk of suicidal thoughts and actions with antidepressant edicines. Talk to your, or your family member�s, healthcare provider about:

� all risks and benefits of treatment with antidepressant medicines

� all treatment choices for depression or other serious mental illness

What is the most important information I should know about antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions?

1. Antidepressant medicines may increase suicidal thoughts or actions in some

children, teenagers, and young adults when the medicine is first started.

2. Depression and other serious mental illnesses are the most important causes of

suicidal thoughts and actions. Some people may have a particularly high risk of

having suicidal thoughts or actions. These include people who have (or have a family

history of) bipolar illness also called manic-depressive illness) or suicidal thoughts or actions.

How can I watch for and try to prevent suicidal thoughts and actions in myself or a

family member?

� Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is first started or when the dose is changed.

� Call the healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.

� Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Call a healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:

� thoughts about suicide or dying

� attempts to commit suicide

� new or worse depression

� new or worse anxiety

� feeling very agitated or restless

� panic attacks

� trouble sleeping (insomnia)

� new or worse irritability

� acting aggressive, being angry, or violent

� acting on dangerous impulses

� an extreme increase in activity and talking (mania)

� other unusual changes in behavior or mood