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Doxepin 50mg Capsules - Generic Sinequan
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Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using Doxepin outweigh the risks.

Family and caregivers must closely watch patients who take Doxepin . It is important to keep in close contact with the patient's doctor. Tell the doctor right away if the patient has symptoms like worsened depression, suicidal thoughts, or changes in behavior. Discuss any questions with the patient's doctor.

Doxepin is used for:

Treating depression or anxiety in certain patients. Doxepin may also be used for other conditions as determined by your doctor.

Doxepin is a tricyclic antidepressant. Doxepin is not known exactly how it works. Doxepin may increase the activity of certain chemicals in the brain, which help elevate mood.

Do NOT use Doxepin if:

  • you are allergic to any ingredient in Doxepin or to other tricyclic antidepressants
  • you have certain prostate problems (eg, asymptomatic prostatic hypertrophy), glaucoma, or trouble urinating
  • you are taking clonidine, an H1 antagonist (eg, astemizole, terfenadine), or ibutilide, or you have taken a monoamine oxidase inhibitor (MAOI) (eg, furazolidone, phenelzine, isocarboxazid) within the past 14 days

 

Before using Doxepin :

Some medical conditions may interact with Doxepin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of heart problems, seizures (eg, epilepsy), overactive thyroid, prostate problems (eg, benign prostatic hypertrophy [BPH]), blood problems (eg, porphyria), other mental or mood problems, suicidal thoughts or attempts, or alcohol abuse

Some MEDICINES MAY INTERACT with Doxepin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antiarrhythmics (eg, quinidine, propafenone, flecainide), antifungal medicines (eg, fluconazole, terbinafine), carbamazepine, cimetidine, mibefradil, phenothiazines (eg, chlorpromazine, thioridazine), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, sertraline) because they may increase the risk of Doxepin 's side effects
  • Anticoagulants (eg, warfarin), H1 antagonists (eg, astemizole, terfenadine), ibutilide, sulfonylureas (eg, tolazamide, glipizide), sympathomimetics (eg, phenylephrine, pseudoephedrine), or tramadol because the risk of their side effects may be increased by Doxepin
  • Clonidine, guanadrel, guanethidine, or guanfacine because their effectiveness may be decreased by Doxepin
  • MAOIs (eg, furazolidone, phenelzine, isocarboxazid) because severe toxic effects may occur

 

How to use Doxepin :

Use Doxepin as directed by your doctor. Check the label on Doxepin for exact dosing instructions.

  • Doxepin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Doxepin refilled.
  • Take Doxepin by mouth with or without food.
  • Taking Doxepin at bedtime may help reduce side effects (eg, daytime drowsiness). Discuss this possibility with your doctor.
  • If you miss a dose of Doxepin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you take 1 dose daily at bedtime, do not take the missed dose the next morning.

 

Important safety information:

  • Doxepin may cause drowsiness, dizziness, blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Doxepin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Doxepin will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Doxepin may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Limit your alcohol consumption while taking Doxepin .
  • Children, teenagers, and young adults who take Doxepin may be at increased risk for suicidal thoughts or actions. Watch all patients who take Doxepin closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
  • Doxepin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Doxepin . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Tell your doctor or dentist that you take Doxepin before you receive any medical or dental care, emergency care, or surgery.
  • After you start taking Doxepin , several weeks may pass before you feel the full benefit.
  • Use Doxepin with caution in the ELDERLY; they may be more sensitive to its effects.
  • Doxepin should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doxepin while you are pregnant. Doxepin is found in breast milk. Do not breast-feed while taking Doxepin .

Possible side effects of Doxepin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; constipation; diarrhea; dizziness; drowsiness; dry mouth; excess sweating; headache; heartburn; increased appetite; indigestion; nausea; unpleasant taste; urinary retention; vomiting; weakness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal movements; aggressive or bizarre behavior; agitation; anxiety; blurred vision or other vision changes; chest pain; difficulty speaking and swallowing; disorientation; eye pain; fainting; fast, slow, or irregular heartbeat; hair loss; hallucinations; hostility; irritability; loss of balance; mood swings; nervousness or restlessness; panic attacks; ringing in the ears; seizures; shakiness; sore throat or fever; trouble sleeping; twitching of the face or tongue; unusual bleeding or bruising; yellowing of the skin or eyes.

 

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