Chemical Name: SULFAMETHOXAZOLE (sul-fa-meth-OX-a-zole) and TRIMETHOPRIM (trye-METH-oh-prim)
Sulfamethoxazole is an antibiotic combination used to treat or prevent infections.
Some medicines or medical conditions may interact with Sulfamethoxazole. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE Sulfamethoxazole if you are also taking astemizole, cisapride, or terfenadine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking cyclosporine, dapsone, macrolide antibiotics, methotrexate, warfarin, or medicine for diabetes or seizures. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about taking Sulfamethoxazole.
Follow the directions for using Sulfamethoxazole provided by your doctor. TAKE Sulfamethoxazole with a glass (8 ounces) of water. Drink several additional glasses of water daily unless otherwise directed by your doctor. STORE Sulfamethoxazole at room temperature, away from heat and light. TO CLEAR UP YOUR INFECTION COMPLETELY, continue taking Sulfamethoxazole for the full course of treatment even if you feel better in a few days. Do not miss any doses. IF YOU MISS A DOSE OF Sulfamethoxazole, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to Sulfamethoxazole or any other sulfonamide medicine (such as Septra DS, Bactrim DS, Gantrisin, glyburide, or probenecid), contact your doctor or pharmacist before taking Sulfamethoxazole. A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to Sulfamethoxazole or if a certain medicine is a sulfonamide, contact your doctor or pharmacist. If your symptoms do not improve within a few days or if they become worse, check with your doctor. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. IF YOU WILL BE TAKING Sulfamethoxazole for a long time, keep all appointments with your doctor. Sulfamethoxazole MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun or sunlamps until you know how you react to Sulfamethoxazole. Use a sunscreen or protective clothing if you must be outside for a prolonged period. IF YOU EXPERIENCE difficulty breathing or tightness of chest; swelling of eyelids, face, or lips; or develop a rash or hives, tell your doctor immediately. Do not take any more of Sulfamethoxazole unless your doctor tells you to do so. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using Sulfamethoxazole during pregnancy. Sulfamethoxazole IS EXCRETED IN BREAST MILK. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects
SIDE EFFECTS, that may go away during treatment include stomach upset, nausea, vomiting, or loss of appetite. If they continue or are bothersome, check with your doctor. Rarely, Sulfamethoxazole can cause serious, even fatal, side effects such as a severe peeling skin rash known as Stevens-Johnson syndrome, blood disorders (e.g., agranulocytosis, aplastic anemia), or liver damage. CONTACT YOUR DOCTOR IMMEDIATELY if you experience skin rash or blisters, unusual fatigue, persistent sore throat or fever, yellowing eyes or skin, dark urine, or abdominal pain. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience hives, swelling of the tongue, joint pain, cough, shortness of breath, vaginal irritation or discharge, paleness, unusual bruising or bleeding. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If you take too much
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea or vomiting, stomach pain, dizziness, drowsiness, confusion, depression, blood in urine, and loss of consciousness.
DO NOT SHARE Sulfamethoxazole with others for whom it was not prescribed. DO NOT USE Sulfamethoxazole for other health conditions. KEEP Sulfamethoxazole out of the reach of children. IF USING Sulfamethoxazole FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.