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Chemical Name: ERYTHROMYCIN (eh-rith-roe-MYE-sin) and SULFISOXAZOLE (sul-fi-SOX-a-zole)
This medicine is a macrolide antibiotic and a sulfonamide combination used to
treat infections.
Some medicines or medical conditions may interact with this medicine. INFORM
YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that
you are taking. DO NOT TAKE THIS MEDICINE if you are also taking astemizole,
cisapride, pimozide, terfenadine, or ergot alkaloids. ADDITIONAL MONITORING OF
YOUR DOSE OR CONDITION may be needed if you are taking anticoagulants, buspirone,
carbamazepine, colchicine, cyclosporine, digoxin, disopyramide, methotrexate,
methylprednisolone, midazolam, QT-prolonging agents (medicine that may change
your heart rhythm, such as amiodarone, lithium, phenothiazines, tricyclic
antidepressants, certain quinolone antibiotics, sotalol, bepridil), rifampin,
tacrolimus, theophylline, vinca alkaloids, or medicine for diabetes. Inform your
doctor of any other medical conditions, allergies, pregnancy, or breast-feeding.
Contact your doctor or pharmacist if you have any questions or concerns about
taking this medicine.
Follow the directions for using this medicine provided by your doctor. SHAKE
WELL before taking a dose. IF THIS MEDICINE UPSETS YOUR STOMACH, take it with
food. DRINK PLENTY OF FLUID while you are taking this medicine. Store this
medicine in the refrigerator. Do not freeze. TO CLEAR UP YOUR INFECTION
COMPLETELY, continue taking this medicine for the full course of treatment even
if you feel better in a few days. Do not miss any doses. IF YOU MISS A DOSE OF
THIS MEDICINE, take it as soon as possible. If it is almost time for your next
dose, skip the missed dose and go back to your regular dosing schedule. Do not
take 2 doses at once.
If your symptoms do not improve within a few days or if they become worse, check
with your doctor. THIS MEDICINE MAY CAUSE increased sensitivity to the sun.
Avoid exposure to the sun or sunlamps until you know how you react to this
medicine. Use a sunscreen if you must be outside for a prolonged period. DO NOT
TAKE SELDANE (terfenadine) OR HISMANAL (astemizole) while taking this medicine.
Caution should be used in infants since they may be more sensitive to the
effects of this drug. Though very unlikely to happen, a stomach problem called
IHPS (infantile hypertrophic pyloric stenosis) has been noted. Contact your
child's doctor immediately if the child has persistent vomiting or increased
irritability. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the
benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS
EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine.
SIDE EFFECTS, that may go away during treatment, include stomach cramping,
stomach discomfort, nausea, diarrhea, or loss of appetite. If they continue or
are bothersome, check with your doctor. Rarely, this medicine can cause serious,
even fatal, side effects such as a severe peeling skin rash known as Stevens-
Johnson syndrome, blood disorders (e.g., agranulocytosis, aplastic anemia), or
liver damage. CONTACT YOUR DOCTOR IMMEDIATELY if you experience skin rash or
blisters, unusual fatigue, persistent sore throat or fever, yellowing eyes or
skin, dark urine, or abdominal pain. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE
if you experience vomiting, itching, vaginal irritation or discharge. If you
notice other effects not listed above, contact your doctor, nurse, or
pharmacist.
Drug interactions can result in unwanted side effects or prevent a medicine from
doing its job. Use our drug interaction checker to find out if your medicines
interact with each other.
Check drug interactions
If overdose is suspected, contact your local poison control center or emergency
room immediately. Symptoms of overdose may include loss of appetite, nausea,
vomiting, dizziness, drowsiness, and headache.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT
USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the
reach of children.
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