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Pramipexole DI-HCL 0.25 mg Tablet - Generic Mirapex
*A prescription is required from your doctor. See How to Order., Online Drug & Prescription Services, Toledo, OH
**Select (below) the quantity authorized on your prescription.**
Quantity: Our Price  
90 tablets $7.75  
100 tablets $8.17  
270 tablets $22.09  
360 tablets $29.45  
450 tablets $36.81  
540 tablets $44.18  

Pramipexole DI-HCL is used for:

Treating the signs and symptoms of Parkinson disease. Pramipexole DI-HCL is also used to treat restless legs syndrome (RLS). Pramipexole DI-HCL may also be used for other conditions as determined by your doctor. Pramipexole DI-HCL is a dopamine agonist. It is thought that the shaking (tremors) of Parkinson disease is caused by reduced amounts of the chemical transmitter dopamine in the brain. Exactly how Pramipexole DI-HCL works is unknown, but it may stimulate the dopamine receptors in the brain.

Do NOT use Pramipexole DI-HCL if:

  • you are allergic to any ingredient in Pramipexole DI-HCL

Before using Pramipexole DI-HCL :

Some medical conditions may interact with Pramipexole DI-HCL . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, ordietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems, low blood pressure, or daytime sleepiness
  • if you drink alcohol or have a history of compulsive behavior (eg, eating, gambling, shopping)
Some MEDICINES MAY INTERACT with Pramipexole DI-HCL . Tell your health care provider if you are taking any other medicines, especially any of the following:
  • Cimetidine, diltiazem, quinidine, quinine, ranitidine, triamterene, or verapamil because they may increase the risk of Pramipexole DI-HCL 's side effects
  • Levodopa because the risk of its side effects may be increased by Pramipexole DI-HCL
  • Butyrophenones (eg, haloperidol), metoclopramide, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease Pramipexole DI-HCL 's effectiveness

How to use Pramipexole DI-HCL :

Use Pramipexole DI-HCL as directed by your doctor. Check the label on the medicine for exact dosing instructions.
  • An extra patient leaflet is available with Pramipexole DI-HCL . Talk to your pharmacist if you have questions about this information.
  • Take Pramipexole DI-HCL by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Your dose will be started low and gradually increased to achieve the best results. Do not change your dose sooner than recommended.
  • Do not suddenly stop taking Pramipexole DI-HCL without checking with your doctor. Severe side effects, including fever, mental or mood changes, and stiff muscles, may occur.
  • If you miss a dose of Pramipexole DI-HCL , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss several doses, contact your doctor before you start to take Pramipexole DI-HCL again.

Important safety information:

  • Pramipexole DI-HCL may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Pramipexole DI-HCL with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Pramipexole DI-HCL ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Pramipexole DI-HCL may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Some patients who take Pramipexole DI-HCL have reported suddenly falling asleep while performing daily activities (eg, driving, eating, conversing). Many patients reported drowsiness before falling asleep. However, some patients did not experience drowsiness and felt that they were alert immediately before suddenly falling asleep. Use caution when driving, operating machinery, or performing other activities that could be dangerous. Inform your doctor if you experience unusual drowsiness or sleepiness while using Pramipexole DI-HCL .
  • If you are taking Pramipexole DI-HCL for RLS, contact your doctor if you experience new or worsening symptoms, especially in the early morning hours.
  • Some people have experienced new, unusual, or increased urges (eg, gambling, sexual urges) while using Pramipexole DI-HCL . Tell your doctor right away if you notice such effects.
  • Patients with Parkinson disease may have an increased risk of developing a certain type of skin cancer (melanoma). It is not known if Pramipexole DI-HCL also increases the risk of melanoma. You may need to have skin exams while you are using Pramipexole DI-HCL . Discuss any questions or concerns with your doctor.
  • Lab tests, including blood pressure or skin checks, may be performed while you use Pramipexole DI-HCL . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Pramipexole DI-HCL with caution in the ELDERLY; they may be more sensitive to its effects, especially hallucinations.
  • Pramipexole DI-HCL should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pramipexole DI-HCL while you are pregnant. It is not known if Pramipexole DI-HCL is found in breast milk. Do not breast-feed while taking Pramipexole DI-HCL .

Possible side effects of Pramipexole DI-HCL :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Abnormal dreams; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; stuffy nose; tiredness; trouble sleeping; upset stomach; weakness. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal thinking; change in behavior, mood, or emotions; chest pain; confusion; decreased sexual ability; difficulty walking; fainting; hallucinations; increased urination; memory loss; muscle pain, tenderness, or weakness; new or unusual skin growths; severe or persistent drowsiness or sleepiness; shortness of breath; sudden irresistible urge to sleep or suddenly falling asleep at unusual times; swelling of the arms or legs; trouble swallowing; unusual or intense urges (eg, gambling, sexual urges); unusual twitching or muscle movements; vision changes; vivid dreams or daydreams.


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Secure Socket Layer, Online Drug & Prescription Services, Toledo, OH
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 Toledo, OH 43617
 Phone: 1-(866) 499-1940
 Fax: 1-(866) 515-9591