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Indomethacin - 25mg Capsule
*A prescription is required from your doctor. See How to Order.
PrescriptionGiant.com, Online Drug & Prescription Services, Toledo, OH
**Select (below) the quantity authorized on your prescription.**
Quantity: Our Price  
60 capsules $5.99  
90 capsules $8.54  
120 capsules $11.38  
150 capsules $14.23  
180 capsules $17.07  
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Indomethacin Capsules are a nonsteroidal anti-inflammatory drug (NSAID). Indomethacin may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take Indomethacin Capsules for a long time. Do not use Indomethacin Capsules right before or after bypass heart surgery.

Indomethacin Capsules may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.

Indomethacin Capsules are used for:

Treating moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is used to treat gout or certain types of bursitis and tendonitis. Indomethacin may also be used for other conditions as determined by your doctor.

Indomethacin Capsules are an NSAID. Exactly how it works is not known. Indomethacin may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Do NOT use Indomethacin Capsules if:

  • you are allergic to any ingredient in Indomethacin Capsules
  • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)
  • you have recently had or will be having bypass heart surgery
  • you are taking diflunisal, another NSAID (eg, ibuprofen), or triamterene
  • you are in the last 3 months of pregnancy

Before using Indomethacin Capsules:

Some medical conditions may interact with Indomethacin Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers, inflammation)
  • if you have a history of swelling or fluid buildup, depression, mental or mood problems, seizures, Parkinson disease, asthma, growths in the nose (nasal polyps), or mouth inflammation
  • if you have high blood pressure, a blood disorder, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases
  • if you have poor health, dehydration or low fluid volume, low blood sodium levels, or high blood potassium levels, you drink alcohol, or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Indomethacin Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), diflunisal, heparin, other NSAIDs (eg, ibuprofen), salicylates (eg, aspirin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased
  • Potassium-sparing diuretics (eg, spironolactone, triamterene) because the risk of kidney problems or increased blood potassium levels may be increased
  • Cyclophosphamide because low blood sodium levels may occur
  • Probenecid because it may increase the risk of Indomethacin Capsules's side effects
  • Cyclosporine, digoxin, lithium, methotrexate, quinolones (eg, ciprofloxacin), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Indomethacin Capsules
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Indomethacin Capsules

How to use Indomethacin Capsules:

Use Indomethacin Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Indomethacin Capsules comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Indomethacin Capsules refilled.
  • Take Indomethacin Capsules by mouth with food. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor if you have persistent stomach upset.
  • Take Indomethacin Capsules with a full glass of water (8 oz/240 mL) as directed by your doctor.
  • If you miss a dose of Indomethacin Capsules and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Important safety information:

  • Indomethacin Capsules may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Indomethacin Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Serious stomach ulcers or bleeding can occur with the use of Indomethacin Capsules. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Indomethacin Capsules with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Indomethacin Capsules are an NSAID. Before you start taking any new medicine, read the ingredients. If it also has an NSAID (eg, ibuprofen) in it, check with your doctor. If you are not sure, check with your doctor or pharmacist.
  • Do not take aspirin while you are using Indomethacin Capsules unless your doctor tells you to.
  • Indomethacin Capsules may interfere with certain lab tests. Be sure your doctor and lab personnel know that you take Indomethacin Capsules.
  • Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Indomethacin Capsules with caution in the ELDERLY; they may be more sensitive to its effects, including stomach bleeding, kidney problems, confusion, or mental changes.
  • Indomethacin Capsules should be used with extreme caution in CHILDREN younger than 15 year old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Indomethacin Capsules may harm the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Indomethacin Capsules while you are pregnant. Indomethacin Capsules are found in breast milk. Do not breast-feed while you are taking Indomethacin Capsules.

Possible side effects of Indomethacin Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; rectal bleeding; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; unusual vaginal bleeding; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

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