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Chemical Name: QUINAPRIL (KWIN-a-pril) and HYDROCHLOROTHIAZIDE (hye-droe-klor-oh-THYE-a-zide)
This medicine is an ACE inhibitor and thiazide diuretic combination used to treat high blood pressure. It may also be used to treat other conditions as determined by your doctor.
WARNING: When used during the second and third trimesters of pregnancy, the quinapril in this medicine can cause injury and death to the fetus. Consult your doctor or pharmacist for more information. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking dofetilide or ketanserin. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking clozapine, diazoxide, digitoxin, digoxin, indomethacin, lithium, potassium, diuretics, azathioprine, or medicine for diabetes. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a history of kidney artery narrowing. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for using this medicine provided by your doctor. This medication is best taken on an empty stomach (one hour before or two hours after a meal), or with a light meal. High-fat meals, however, may decrease the absorption of the medicine into your bloodstream. Take it exactly as prescribed and try to take it at the same time each day. THIS MEDICINE MAY CAUSE an increase in urine or in frequency of urination. To prevent this from affecting sleep: if you are taking 1 dose daily, take it in the morning after breakfast. If you are taking more than 1 dose daily, take the last dose no later than 6 pm. STORE THIS MEDICINE at room temperature below 77 degrees F (25 degrees C), away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to this medicine or any other sulfonamide medicine (such as Septra DS, Bactrim DS, Gantrisin, glyburide, or probenecid), contact your doctor or pharmacist before taking this medicine. A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to this medicine or if a certain medicine is a sulfonamide, contact your doctor or pharmacist. DO NOT STOP TAKING THIS MEDICINE without discussing it with your doctor. If you are taking a tetracycline antibiotic or a quinolone antibiotic (e.g., ciprofloxacin, levofloxacin), take it at least 3 hours apart from this medicine. This product contains magnesium which can interfere with absorption of these antibiotics. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. THIS MEDICINE MAY CAUSE DIZZINESS, lightheadedness, or fainting. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness. THIS MEDICINE MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of this medicine unless your doctor tells you to do so. DO NOT USE A SALT SUBSTITUTE or potassium supplement without checking with your doctor. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor. FOR WOMEN: USE OF THIS MEDICINE DURING PREGNANCY has resulted in fetal and newborn death. If you think you may be pregnant, contact your doctor immediately. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine. IF YOU HAVE DIABETES, this medicine may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
SIDE EFFECTS that may occur while taking this medicine include nausea, vomiting, diarrhea, headache, dry cough, dizziness or lightheadedness when sitting up or standing, loss of appetite, or fatigue. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience rash or itching, muscle pain or cramps, vomiting, restlessness, dry mouth, unusual thirst, unusual tiredness or weakness, fast heartbeat, yellowing of the skin or eyes, sore throat or fever, or drowsiness. CONTACT YOUR DOCTOR IMMEDIATELY if you experience irregular or slow heartbeat; chest pain; unusual stomach pain; swelling of hands, face, lips, eyes, throat, or tongue; or difficulty swallowing or breathing. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, weakness, dry mouth, excessive urination followed by a decrease in amount of urine, muscle cramps, and weak or irregular heartbeat.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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